Inaugural Meeting of Kavli INsD, Oxford’s Scientific Advisory Board

Inaugural Meeting of Kavli INsD, Oxford’s Scientific Advisory Board

Kavli INsD, Oxford held its first Scientific Advisory Board (SAB) meeting on 21 November  2023. The meeting was chaired by Professor Wolfgang Baumeister, Director, Max Planck Institute of Biochemistry, Munich with other members and their affiliations listed on our website.

 

sab members

 

The day began with an overview and introduction to Kavli INsD by Kavli Oxford Director, Carol Robinson who said,

 

“I was proud to be able to present our institute to the SAB and have in attendance heads of both divisions as well as many heads of departments”

 

philipp kukura presenting
lindsay baker presenting

 

Scientific sessions begun with Philipp Kukura who introduced Mass Photometry and the highs and lows of running a spin out company.  Lindsay Baker, our first Oxford Kavli Fellow now appointed as an Associate Professor, then shared her fellowship experiences.

 

The spotlight then turned to this year's KARD Awardees, who described their ground-breaking research proposals. The morning session was completed by Richard Wade-Martins, who presented his lab's research on Parkinson's, Alzheimer's, and Dementia.

 

corinne lutomski presenting  kard awardee
akansha mehta presenting  kard awardee

 

 

richard wade martins presenting

 

 

Board Members, visiting Heads of Division and Departments then joined the Kavli community in our open atrium to listen to our customary ‘3-minute research presentations’ 1

 

During the lunch break 22 posters and one award winning scientific image provided an opportunity for postdocs and DPhil students to present their research and engage with board members.2

 

poster session

 

The afternoon session featured further research presentations; first from Wellcome Trust Sir Henry Dale Fellow Dominika Gruzska on investigating genome dynamics during DNA replication; Molly Stevens who recently joined Kavli Oxford from Imperial College, then emphasised the importance of collaborative science in bionanoengineering. Next up Simon Newstead, delved into structural biochemistry and molecular-level understanding of nutrient transporters. Esther Becker closed the session by shedding light on her research on ataxia.

 

dominika gruszka presenting
molly stevens presenting

 

 

simon newstead presenting
esther becker presenting

 

Kavli Oxford thanks all Scientific Advisory Board members for their valuable time and our Kavli researchers for their presentations. The event marked a significant milestone in our research progress at Kavli Oxford. We look forward to hosting the Board at future meetings and engaging with their constructive challenges and feedback.


1. 

Dr Hafez El-Sayyed (Physics) presented on antimicrobial resistance and citizen science

Dr Carla Kirschbaum (Chemistry)  presented on mass spectrometry

Dr Emma Silvester (Biochemistry) presented on Cryo-EM

Dr Maria-Claudia Caiazza (Physiology, Anatomy and Genetics) and DPhil candidate, Sacha Salphati presented on their collaborative work on Parkinson’s Disease and synthetic nanobodies

2. 
RESEARCHER TITLE
Apsley, Elizabeth Modeling human Purkinje cell development using iPSC
derived cerebella organoids
Bafna, Akansha The dynamic gene regulatory landscape of the brain in
response to sleep deprivation
Burnap, Sean The development of glycan-protein cross-linking mass
spectrometry to investigate host-pathogen interactions
Calvaresi, Valeria Hydrogen-deuterium exchange mass spectrometry with
integrated glxcenceteemiss for the analysis of viral
glycoproteins
Cole, Bethan Preclinical development of TRPC3 inhibitors to treat
spinocerebellar ataxia
Esser, Tim Near-atomic gas-phase structure of B-galactosidase
produced by combining native electrospray ion beam
deposition (ESIBD) and cryo-EM
Farrell, Brendan The PiRCR, complex bridges malaria parasite and
erythrocyte during invasion
Farrimond, Lucy Optogenetic stimulation reveals activity-dependent
mechanisms of neurodegeneration in C90rf72-HRE ALS
motor neurons and neuromuscular co-culture
Gatford, Nick Image showing a culture of human dopaminergic neurons
generated from human stem cells
Heon-Roberts, Rachel A dual CRISPRi and microscopy approach to investigate the
effects of aggregating proteins in neurodegeneration
Jamwal, Abhishek Structural basis for IL-33 recognition and its antagonism by
a hookworm effector HpARI
Kalmankar, Neha Integrating Mass Spectrometry with Molecular Dynamics
Simulations for Modeling IRMPD Fragmentation of
Membrane Proteins
Kaplan, Merve The molecular specificity of benacanase and its role in viral
infection
Lin, Yifei (Abby) Structural basis for PI3,5P2 regulation of the lysosomal
chloride: proton antiporter CLC7
Oluwole, Abraham Interrogating antimicrobial drug targets by native mass
spectrometry
Rowland, Helen iPSC Astrocyte Morphology Reflects Patient Clinical
Markers
Salphati, Sacha Synthetic Nanobodies to Investigate the Role of lon
Channels and Transporters in Lysosomal Homeostasis and
Diseases
Thiele, Christoph Single Molecule Optical Holography
Turner, Piers
+
Chatzimichail, Stelios
Rapid detection of pathogenic bacteria and their
antimicrobial resistance using microfluidics, microscopy
and machine-learning
Thomas-Wright, Iona Characterising extracellular a-synuclein and its release
mechanisms in Parkinson's iPSC-dopamine neurons
Xu, Yinyan Dynamic Translational Profile of Stressed iPSC-MNs from
C9orf72-ALS Patients by Translating Ribosome Affinity
Purification (TRAP)
Yan, Shijun a-Synuclein in Serum L1CAM-Positive Extracellular Vesicles
as a predictive biomarker for Parkinson's disease pathology
Zhang, Linlin Guiding Antiviral Discovery against Filoviruses via
Glycosylation Analysis of Viral Spikes